BENEFITS FOR MEN – LEAN MUSCLE MASS BUILDING & MORE* DIM acts as an Estrogen Blocker inhibits the Aromatase enzyme that converts testosterone into estrogen and helps prevent estrogen dominance, providing natural testosterone support. Due to a lack of research in humans, little is known about the long-term safety and side effects of DIM supplements. This week, I'd like to talk to you about DIM. Such individuals should steer clear of DIM supplements unless under the supervision of a medical professional. It is being studied for its anticancer properties While some show severe symptoms, many remain asymptomatic. Some other possible side effects from this supplement include vomiting, headaches, nausea, rashes, and hyponatremia. Still, you may wonder whether these uses are backed by scientific evidence. DIM is thought not to have goitrogenic properties. Research suggests that DIM affects estrogen levels in your body (1). Some people use DIM supplements to help them lose weight, and … Thus, you should talk to your healthcare provider before taking DIM supplements. While testosterone is known as a male hormone, it is also produced in a woman’s body, but instead, it converts into estrogen. DIM stimulates more efficient metabolism for estrogen, meaning it helps regulate the ratio of healthy to less healthy estrogen. Do you want the best of science-backed health & nutrition information in your inbox? Limited studies suggest that DIM supplements may help reduce prostate enlargement and protect against certain cancers. Before adding a DIM supplement to your diet, be sure to speak with your doctor about any risks or potential interactions. Kid Influencers Promoting Junk Food On YouTube, Study Finds, Study Shows How Musical Training Improves Cognitive Function, Study Reveals Why Some People Show Severe COVID Symptoms, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059820/, https://www.worldscientific.com/doi/abs/10.1142/9789814719094_0005, https://academic.oup.com/mend/article/23/12/1940/2684044, https://www.researchgate.net/profile/Jianbin_Zheng/publication/8572652_Anticarcinogenic_and_antioxidant_activity_of_diindolylmethane_derivatives/links/55c371a308aea2d9bdc17302/Anticarcinogenic-and-antioxidant-activity-of-diindolylmethane-derivatives.pdf, https://www.antiaging-systems.com/articles/209-estrogen-the-unrecognized-male-hormone, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759426/, https://books.google.com/books?id=geSVDgAAQBAJ, 12 Proven Health Benefits of Apple Cider Vinegar, Hibiscus Tea: Benefits, How to Make, & Side Effects, Calamansi Juice: Benefits, Recipe, and Side Effects. Estrogen dominance can have a negative effect on both mental and physical health of women, so using DIM to control estrogen levels and mitigate PMS symptoms is a very common practice, although there is a lack of concrete evidence supporting this correlation. Benefits of DIM Supplements. In general, DIM’s ability to prevent large increases or decreases in estrogen can help with a number of issues, including acne, menopause symptoms, weight gain and even cancer. And then one day, I read about a supplement I hadn’t tried called DIM—diindolylmethane, if we’re being formal—that supposedly works like a charm for hormonal breakouts. A study carried out by the…. However, it is not a plant estrogen or an estrogen mimic, like soy isoflavones. Although it’s not associated with serious side effects, it interacts with hormones and affects genes involved in cancer. Diindolylmethane supplements—DIM for short—have been credited with combatting breakouts and other period problems. As a result, people looking to treat a specific condition like acne or prostate issues may seek a concentrated dose in the form of a DIM supplement. Diindolylmethane (DIM) is a versatile nutraceutical for which I find many uses in my practice. Traditionally used as an add-on to prevent the recurrence of a rare respiratory disease, this compound is now being investigated as a cancer-preventing agent. Therefore, a recommended dose from a supplement would look more like 100 to … The powerful health benefits of dates include providing an energy boost, increasing iron in the body, and aiding digestion.Â. DIM supplements is commonly taken in doses of 100 mg to 200 mg. However, their effectiveness for other hormone-related conditions hasn’t been widely studied. As a supplement, Diindolylmethane comes with many benefits for the human body. These amounts can increase three to four times on an individual basis to derive needed benefits for hormone balance and metabolism. DIM has been shown to provide potential protection against hormone-dependent cancers such as breast, uterus and cervical cancer. This is necessary because it will be hard to consume enough cruciferous vegetables in order to get just 10-30 mg of DIM daily. DIM supplements have not been shown to cause serious side effects, though more safety research is needed. There is a compound in cruciferous vegetables, called indole-3-carbinol, which will break down to diindolylmethane during the digestive process and be used by the body for a number of essential purposes. So, the benefits of taking DIM are so many, that every woman can benefit from it. It may help to support acne relief, healthy menopause, and prostate health. Curcumin can also limit weight gain. DIM can mitigate the level of estrogen in the body by stimulating the breakdown of estrogen in beneficial metabolites. DIM was found to be more stable and more suitable for use in supplements. Adding DIM supplements to your diet can help to strengthen the reactivity and response time of your immune system, among others, despite the relative dearth of conclusive research on the subject. Ginger also helps boost bone health, strengthen the immune system, and increase appetite. DIM is derived from cruciferous vegetables like Broccoli. A yearlong study gave 130 women with breast cancer on tamoxifen therapy either a placebo or 150 mg of DIM twice a day. In preliminary research, some scientists have found that diindolylmeth… All rights reserved. Your hormones underlie many basic processes in your body. However, in a 6-month study in 551 women with cervical abnormalities, taking 150 mg of DIM per day had no effect on cervical cell changes (3, 13). Diindolylmethane, or DIM, is a natural chemical formed in your digestive tract from a compound called glucobrassicin, which is contained in cruciferous vegetables such as broccoli, cauliflower and cabbage. Those given DIM experienced significant improvements in prostate health, as well as PIN (14). Benefits of calamansi juice include bleaching the skin, detoxifying the body, aiding in weight loss & managing diabetes. Always use scissors or pruning shears to make clean cuts. Find out about natural and pharmaceutical…, Estrogen is one of the sex hormones that is responsible for women's reproduction abilities. One study analyzes the effect of DIM on 130 women with breast cancer over 12 months. The entire list of reference links is also provided at the bottom of the article. Before taking these supplements, get dosage guidance from your healthcare provider. Estrogen Metabolism Benefits of DIM Plus Estrogen metabolism can have a positive effect on acne and other skin issues. Benefits are a lot, a few proved with research and others are still being studied. To increase transparency to the user, we provide reference links marked by numbers in parentheses in the copy of the article. But there’s no proof DIM actually works for endurance or sexual performance. The therapeutic dose of DIM that most experts recommend is 100 to 200 mg each day. Also, the DIM supplement additionally influences testosterone, a hormone that is connected to zits. However, a study in 24 healthy people found that although DIM doses of up to 200 mg were well tolerated and didn’t cause side effects, one person experienced nausea, headache, and vomiting after taking a 300-mg dose, suggesting that higher doses may be associated with adverse side effects (15). But the precise reasons behind this are less known. It is also commonly used as preventative medicine for cancer by non-traditional healers, due to its purported anti-cancer effects. Read on to find out about the health benefits of DIM for your whole family. This article provides a comprehensive overview of DIM supplements, including their benefits and side effects. Negative interactions with diuretic medications and liver medications have also been reported, as DIM may speed up how quickly medications are broken down in the liver. We are still learning more about the powerful effects of this plant-based nutrient, but here are a few of the science-backed benefits. ✓ Evidence Based. They’re also used to help prevent prostate enlargement, treat acne, aid weight loss, and reduce premenstrual syndrome (PMS) and menopause symptoms. Resources and Additional Reading: © 2005-2020 Healthline Media a Red Ventures Company. DIM ameliorates experimental liver fibrosis induced by thioacetamide in mice [ 35 ]. When NOT to Use DIM. Having too much estrogen in the body can increase the risk of breast cancer, along with cervical cancer and ovarian cancer. But this does not mean that DIM is always safe in supplemental form. There are a number of positive effects of DIM in the body, but there has been a decided lack of research on this substance or its potential impact on long-term health. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, PMS Supplements: 7 Options for Mood Swings and Other Symptoms, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 7 Foods for Lowering Estrogen Levels in Men, Natural and Pharmaceutical Estrogen Blockers for Men, 12 Natural Ways to Boost Estrogen in Your Body, Our Favorite Healthy Finds: Organic Beauty Products for Acne-Prone Skin. The same can be said about vegetables that contain Diindolylmethane. Many of the published studies on the benefits of DIM have used BioResponse DIM because generic DIM (ie. Diindolylmethane Benefits May Help Prevent Cancer. Nonetheless, further studies are needed — particularly for uses related to acne, weight loss, and PMS symptoms, which aren’t currently backed by human research. Some websites say DIM can even help with sexual function in both men and women. If yes, please share your email to subscribe. It will likewise urge estrogen to separate into the ‘great’ metabolites as opposed to the ‘terrible’ ones. A 30-day study in 19 post-menopausal women with early-stage breast cancer found that taking 108 mg of DIM per day also resulted in beneficial changes in estrogen levels (9). DIM may have anti-cancer effects. Vitamonk Nutri DIM Supplement still provides ample benefits like helping with menopause symptoms and balancing hormone levels like most others on the list. On a perpetual journey towards the idea of home, he uses words to educate, inspire, uplift and evolve. The fact that DIM can stimulate the breakdown of estrogen into healthy byproducts means that it is a promising complementary treatment to cancer, but more research is required, beyond the work of Dr. Thomson, Ho, and Strom in Nutrition Reviews. Less common side effects include nausea, vomiting, diarrhea, and skin rash (3). DIM might even prevent cancer and acne. not the BioResponse version) is not absorbed very well (or at least this is claimed by BioResponse). First, you will have to discard the tough outer leaves of the lemongrass stalks by peeling them away with your fingers. DIM supplements are attracting a lot of attention recently as they have been touted to have properties that could minimize the risk of cancer. Photo Credit: Shutterstock. As mentioned above, the primary natural sources of DIM (diindolylmethane) is cruciferous vegetables, such as: There has been no clear evidence that using DIM supplements is dangerous or has an implicit risk, but certain side effects have been reported when the supplement is not taken in moderation, or in conjunction with other medications. All the same, studies link an imbalance of estrogen — either too much or too little — to an increased risk of weight gain in both men and women (16, 17, 18). Experts remind us that more clinical trials are required to get a better understanding of how DIM reacts with prescription drugs, but the direction of travel is clear: DIM is safe in recommended doses and effective for the majority of people who are taking it. Our website services, content, and products are for informational purposes only. When you chew raw or lightly cooked cruciferous vegetables, plant enzymes are activated, which allows Diindolylmethane (DIM) to enter your body. No matter DIM’s effectiveness, it’s always good to eat more cruciferous veggies. While it’s predominately lauded for its hormone support benefits, DIM has been picking up steam for its metabolic benefits too. In human research, doses typically range from 108–900 mg per day — though these studies were only related to treatments for cancer and prostate enlargement (8, 9, 14). If you suffer from hormone-related conditions, the addition of more estrogen-like compounds could exacerbate the problems, such as in the case of endometriosis, ovarian cancer or uterine fibroids. Average rating 5.0 out of 5.0 based on 2 user(s). Some of the benefits being researched include a positive impact on cancerous cell growth, reduction in acne, prevention of an enlarged prostate, and treatment of the premenstrual syndrome. As stated in Clinical Naturopathy: In Practice, by regulating the levels of both testosterone and estrogen, it can help to reduce hormonal breakouts of acne, particularly those that occur around the time of menstruation in so many women, a condition known as cystic acne. DIM supplements are purported to aid other hormone-related conditions. As it affects estrogen levels, DIM may help treat a variety of conditions, including hormone-sensitive cancers and prostate issues. You can continue to get DIM through eating cruciferous vegetables and letting your body do the natural process to produce DIM; but be careful how you cook these vegetables. Diindolylmethane (DIM) is a natural substance found in vegetables like broccoli, cabbage, and cauliflower. The excess can be blotted out gently using a tissue. Diindolylmethane is purported to produce changes in estrogen metabolism, a biological process thought to influence the development of certain hormone-dependent cancers such as breast cancer. In addition to Diindolylmethane, they also have a chemical called indole-3-carbinol. It’s also concentrated and sold as a supplement. Benefits of DIM Supplement. While the exact mechanism is unknown, indole-3-carbinol is thought to be partly responsible (4, 5, 6). The byproduct of this estrogen breakdown process is linked to lower inflammation levels and can control other symptoms related to prostatitis, such as incontinence and other issues related to urination. Although research is ongoing, increasing the ratio of 2-hydrozyestrone to 16-hydrozyesterone may reduce breast cancer risk and cause anti-tumor effects (8). Anti-cancer Properties: Diindolylmethane can prevent and stop certain cancers from developing by controlling estrogen levels. Read more! Notably, a mouse study found that DIM helped prevent cervical cancer. DIM supplements contain diindolymethane, which is found in cruciferous vegetables like broccoli and cabbage. Some of the benefits being researched include a positive impact on cancerous cell growth, reduction in acne, prevention of an enlarged prostate, … › Supplement Ingredients › DIM Health Benefits And Uses Of DIM. If you take a DIM supplement, you’re bypassing these steps but can still take full advantage of the health benefits of DIM. DIM is particularly interesting to researchers because of its estrogen-like qualities, along with its paradoxical abilities to control an excessive amount of estrogen production. You can use Diindolylmethane (DIM) supplements for several health benefits that you can also avail from vegetables like Broccoli. Although DIM is not suitable for everyone, DIM appears to have benefits for both men and women, and DIM side effects are minimal. What helps set it apart is the other unique benefits it provides. It is commonly found in broccoli, and holds promise as being a molecule for anti-cancer effects and as an aromatase inhibitor. This spicy root is also good for mitigating obesity and relief from menstrual pain. What’s more, it contains an optimal do… While cruciferous vegetables are the primary food source of DIM, you would need to eat several servings every day to reap this compound’s benefits (1). Current human research doesn’t show DIM supplements to be toxic or have serious side effects. As we age, our estrogen decreases, which can cause side…, Chemicals may seem like the best route for acne-prone skin, but it’s not your only option. After all, vegetables like broccoli and kale are rich sources of important nutrients, including fiber, antioxidants, vitamins, and minerals. More specifically, DIM (diindolylmethane) is produced when we eat cruciferous vegetables, which are often recommended in a healthy diet. However, human studies are limited (1, 2). An advantage of supplementation with DIM over consumption of large amounts of raw cruciferous vegetables is avoidance of goitrogenic isothiocyanates. The antioxidant and anti-inflammatory properties of turmeric, mainly due to its compound curcumin, is responsible for weight loss. Uses and potential benefits of DIM supplements, Cruciferous Vegetables: Health Benefits and Recipes. Estrogen dominance can play a role in the development of acne because it can lead to oily skin and clogged pores. DIM has been the topic of recent discussions surrounding hormonal health and your menstrual cycle. Therefore, it’s best to talk to your healthcare provider to obtain personalized dosage recommendations based on your intended use. Taking DIM can help with menopause symptoms like weight gain, hot flashes, mood swings, etc. This includes cervical dysplasia and respiratory papillomatosis. Test-tube and animal studies likewise suggest that DIM helps fight prostate cancer. Again, due to the effect that DIM can have on estrogen, including its breakdown into more beneficial metabolites, some men use this supplement to manage their prostate size. Another DIM supplement benefit is it may help treat symptoms of HPV (human papilloma virus). As mentioned above, increased levels of DIM in your system can inhibit the conversion of testosterone to estrogen in men. DIM is a compound your body makes from cruciferous vegetables. Last medically reviewed on July 22, 2020. DIM stimulates more efficient metabolism for estrogen, meaning it helps regulate the ratio of healthy to less healthy estrogen. Diindolylmethane, more commonly abbreviated to DIM, is a beneficial supplement that can help our body regulate itself more efficiently. DIM Supplement normally comes in capsules, sometimes in combination with other supplements to optimize the desired outcome. Here's what you need to know about how they work and if … Learn how to identify the symptoms, what causes it, and more. DIM is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and kale. How to get oil out of clothes? Health benefits of hibiscus tea include its ability to control hypertension & reduce high blood pressure, lower blood sugar levels, & improve liver health. Dates are sweet fruits of the date palm tree. These compounds compete with iodine for binding in the thyroid, potentially contributing to hypothyroidism. It also reduces microbial-induced liver injuries [ 34 ]. In supplement form, DIM is frequently prescribed for survivors of breast, uterine and colorectal cancer. Uses and potential benefits of DIM supplements DIM supplements are being studied for their protective effects against certain cancers. Taking DIM, together with low-calorie calorie diet & exercise can make weight loss easier. Low estrogen is typically seen in younger women and women approaching menopause. last updated - February 05, 2020 DrFormulas® DIM Plus Bioperine Supplement is specially formulated to support hormone balance. In the few clinical studies that have been conducted, it has been suggested that DIM may help prevent the growth of cancer cells — specifically breast cancer cells. Benefits of DIM. Now a new…, COVID-19 shows a wide range of manifestations among those affected. This article reviews 12 actions you can take to help your hormones function optimally. Specifically, DIM may stimulate the production of a less potent, more beneficial form of estrogen known as 2-hydroxyestrone (1). All rice noodles and rice paper wraps are gluten-free as they are made wholly from rice. Organic Facts may receive a portion of revenues if you click on the sponsored ads and links by Google, Ezoic, or the Amazon Affiliate program. Images are provided by Shutterstock & our contributors. Many studies on DIM focus on its cancer preventative abilities. A DIM supplement could help you shed those pesky pounds! Consult a medical practitioner for health problems. Although our bodies are remarkably well-designed machines, there are times when supplementing certain nutrients and natural compounds can aid our overall health, particularly if we are suffering from a disease or recovering from an illness. While these benefits are promising, overall research on DIM’s effectiveness and long-term safety in humans is limited. In a 12-month study, 21 men with high-grade PIN were given either a placebo or 900 mg of DIM per day. Diindolylmethane (DIM) is the compound in cruciferous vegetables that makes experts advise people at risk for breast cancer to eat more cabbage and broccoli as a preventive measure. This supplement helps to free up the bound testosterone, promote lean muscle mass building, support weight management, enhance athletic … Other amazing properties of Diindolylmethane include the fact that you can use it as an anti-inflammatory, antiproliferative, antiviral, anti-angiogenesis, antiandrogenic, antibacterial and even for hormone-balancing! Another benefit of estrogen metabolism is weight loss. If you’re looking for a quality DIM supplement, DrFormulas® DIM Plus BioPerine for Men & Womenprovides a convenient once-daily dose of all the DIM you need. Due to limited research, proper dosages for DIM are unknown. Additionally, DIM has been shown to inhibit an enzyme called aromatase, which converts testosterone to estrogen (1). There have been rare instances when certain rice noodle brands may contain gluten. DIM is an abbreviation for 3,3′-diindolylmethane, which is composed of a methane group with two indole groups attached to it. An average diet will likely contain less than 25 mg of diindolylmethane per day, yet some supplements may offer more than 500mg in a daily dose. Furthermore, DIM supplements may stimulate fat breakdown and inhibit fat cell formation. Every now and then, I like to highlight a particular supplement that my audience may not be aware of, and go in-depth about its uses, benefits, and potential drawbacks. As a result, DIM supplements have been gaining popularity as a potential treatment for a variety of hormone-related conditions, including acne, menopause symptoms, prostate issues, and certain forms of cancer. Cruciferous vegetables are low-calorie, and rich in folate, vitamins C, E, and K, and fiber. Diindolylmethane is used for preventing breast, uterine, and colorectal cancer. Along with eating cruciferous vegetables each day as a part of your Male Fertility Diet, consider a DIM supplement. There is evidence, for example, that DIM supplements may have benefits in preventing colorectal cancer, and DIM can also be used to prevent an enlarged prostate, known as benign prostatic hypertrophy. Test-tube and animal studies indicate that DIM protects against ovarian, prostate, and colon cancers as well. To date, research on the health effects of diindolylmethane is fairly limited. Cut rosemary on the new growth. To get maximum benefit from DIM look for it as a supplement. Low Doses of DIM. He co-founded the literary journal, Sheriff Nottingham, and now serves as the Content Director for Stain’d Arts, a non-profit based in Denver, Colorado. However, it is not a plant estrogen or an estrogen mimic, like soy isoflavones. 2 Keep in mind since pure DIM must be provided in an absorption-enhancing formulation, the dose for DIM specifies the weight of the Absorbable Formulation, which is only one forth DIM. On average 10-20 percent of I3C is metabolized to DIM. How to Use DIM. In fact, it may help combat prostatic intraepithelial neoplasia (PIN), a condition that’s characterized by prostate cell growth and considered to be a precursor to prostate cancer (14). It also prevents prostate cancer and BPH. John Staughton is a traveling writer, editor, publisher and photographer with English and Integrative Biology degrees from the University of Illinois in Champaign-Urbana (USA). The primary natural source of DIM is the digestion of cruciferous vegetables. It is naturally obtained via dietary consumption of cruciferous vegetables. In one study in mice on a high fat diet, 23 mg of DIM per pound (50 mg per kg) of body weight significantly reduced the formation of new fat cells (19). Intriguingly, observational studies associate high cruciferous vegetable intake with a reduced risk of certain cancers, including breast and prostate cancer. DIM can mitigate the level of estrogen in the body by stimulating the breakdown of estrogen in beneficial metabolites. Users have experienced an increase in their sex drive and libido, which isn’t common in other DIM supplements. The DIM supplement helps support the liver detoxification process, improves the procedure of estrogen breakdown. Hormonal acne occurs when there is an unbalance of estrogen levels and an increase in the male hormone, testosterone. Proponents claim that consuming diindolylmethane can help increase your defense against several types of cancer, as well as promote detoxification and support weight loss. Studies associate high cruciferous vegetable intake with a reduced risk of breast cancer cells with cervical cancer converts testosterone estrogen... The desired outcome to less healthy estrogen properties of turmeric, mainly women! Medical professional to a lack of research in humans which are often recommended a! For other hormone-related conditions hasn ’ t common in other DIM supplements contain diindolymethane, which are often in... To estrogen ( 1 ) an increase in the body by stimulating the breakdown of estrogen in body... Responsible for weight loss – most women struggling with seemingly impossible weight loss dates providing. 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